List of Publications from IISER Pune

 

• Preeti Ravindra Bhoge, Rakesh Raigawali, Sandhya Mardhekar, Saurabh Anand, Raghavendra Kikkeri. Synergestic interplay of uronic acid and sulfation composition of heparan sulfate on molecular recognition to activity. Carbohydr Res. 2023 doi: 10.1016/j.carres.2023.108919.

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• Isarel Alshanski I, Shomo Toraskar, Ariel Shitrit, Gordon-Levitan. Prashant Jain, Raghavendra Kikkeri, Mattan Hurevich, Shlomo Yitzchaik. Biocatalysis versus Molecular Recognition in Sialoside-Selective Neuraminidase Biosensing ACS Chem Biol. 2023 18(3), 605-614

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• Ankita Chandra, Preeti Ravindra Bhoge, Chethan Shanthamurthy, Raghavendra Kikkeri. Fluorescent glyco-gold nanocluster induced EGFR mediated targeting of cancer cells. Chem Commun (Camb). 2023 Jan 26;59(9):1213-1216.

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• Sandhya Mardhekar, Balamurugan Subramani, Prasanna Samudra, Priya Srikanth, Virendra Mahida, Preeti Ravindra Bhoge, Suraj Toraskar, Abraham Nixon, Raghavendra Kikkeri. Sulfation of Heparan and Chondroitin Sulfate Ligands Enables Cell-Specific Homing of Nanoprobes. Chemistry. 2023  doi: 10.1002/chem.202202622.

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• Ariel Shitrit, Sandhya Mardhekar, Israel Alshanski, Prashant Jain, Rakesh Raigawali, Chethan Shanthamurthy, Raghavendra Kikkeri, Shlomo Yitzchaik, Mattan Hurevich. Profiling Heparan Sulfate-Heavy Metal Ions Interaction Using Electrochemical Techniques. Chemistry. 2022 doi: 10.1002/chem.202202193.

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• Preeti Bhoge, Sandhya Mardhekar, Suraj Toraskar, Balamurugan Subramani, Raghavendra Kikkeri. Pairing Nanoparticles Geometry with TLR Agonists to Modulate Immune Responses for Vaccine Development. ACS Appl Bio Mater. 2022 5(12), 5675-5681.

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• Chethan D. Shanthamurthy, Ana Gimeno, Shani Leviatan Ben-Arye, Nanjudeswamy Vijendra Kumar, Prashant Jain, Vered Padler-Karavani, Jesus Jimenez-Barbedo, Raghavendra Kikkeri,- “Sulfation code and conformation plasticity of L-Iduronic acid homo-oligosaccharides that mimic the biological functions of heparan sulfate” ACS Chem. Bio. 2021, https://doi.org/10.1021/acschembio.1c00582

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• Balamurugan Subramani, Preeti Madhukar Chaudhary, Raghavendra Kikkeri-“A cell-culture technique to encode glyco-nanoparticles selectivity” Chem. An Asian J. 2021, https://doi.org/10.1002/asia.202101015

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• Deepak Ganesh, Prashant Jain, Chethan D. Shanthamurthy, Suraj Toraskar, Raghavendra Kikkeri- “Targeting selectins mediated biological activities with multivalent probes” Front. Chem. 2021, DOI: 10.3389/fchem.2021.773027

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• Prashant Jain, Chethan D. Shathamurthy, Preeti Madhukar Chaudhari, Raghavendra Kikkeri, - “Rational designing of glyco-nanovehicles to target cellular heterogeneity” Chem. Sci. 2021, 12, 4021-4027.

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• Tal Noy-Porat, Adva Mechaly, Yinon Levy, Efi Makdasi, Ron Alcalay, David Gur, Moshe Aftalion, Reut FAlach, Shani Leviatan Ben-Arye, Shirley Lazar, Ayelet Zauberman, theodor Chitlaru, Shay Weiss, Hagi Achdout, Jonathan D. Edgeworth, Raghavendra Kikkeri, Hasi Yu, Xi Chen, Shmuel Yitzhaki, Shmuel C. Shapira, Vered Padler-Karavani, Ohad Mazor, Ronit Rosenfeld. – “Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice” iScience. 2021, 24, 102479.

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• Prashant Jain, Chethan D. Shanthamurthy, Shani leviathan Ben-Arye, Robert J. Woods, Raghavendra Kikkeri, Vered Padler-karavani. - “Discovery of rare sulfated N-unsubstituted glycosamine based heparan sulfate analogs selectively activating chemokines” Chem. Sci. 2021, 12, 3674-3681.

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•  Prashant Jain, Chethan D. Shanthamurthy, Shani leviathan Ben-Arye, Sharon Yehuda, S. S. Nandikol, H. V. Thulasiram, Vered Padler-Karavani, Raghavendra Kikkeri, - “Synthetic heparan sulfate ligands for vascular endothelial growth factor to modulate angiogenesis” Chem Commun. 2021, 57, 3516-3519.

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•  Chethan D. Shanthamurthy, Shani leviathan Ben-Arye, Nanjundaswamy Vijendra Kumar, S. Yehuda, R. Ramon, Rober J Woods, Vered Padler-Karavani, Raghavendra Kikkeri. – “Heparan sulfate mimetics differentially affect homologous chemokines and attenuate cancer development” J. Med. Chem. 2021, 64, 3367-3380. 

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• Eric Danielson, Micro Dindo, Alexahder J. Parkovick, Pwan Kumar, Zhenwei Wang, Prashan Jain, Trimbak Meta, Zakaria Ziadi, Raghavendra Kikkeri, Paola Laurino, Mukhles Sowwan.-“Non-enzymatic and highly selective lactose detection utilizing graphene field-effect transistors” Biosens Bioelectron. 2020, 165, 112419.

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• Saurabh Anand, Sandhya mardhekar, Rakesh Raigawali, Nirmala Mohanta, Prashanth Jain, Chethan D. Shanthamurthy, Boopathy Gnanaprakasam and Raghavendra Kikkeri. - Org. Lett. 2020, 22, 3402-3406.

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• Chethan D. Shanthamurthy, Raghavendra Kikkeri. - “Linear synthesis of de novo oligolduronic acid”. Eur. J. Org. Chem. 2019, 2950-2953.

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• Balamurgan Subramani, Chethan D. Shanthamurthy, Parag Maru, Menakshi Belakar, Sandhya Mardekar, Dhanasekaran Shanmugam, Raghavendra Kikkeri. - “Demystifying a hexuronic acid ligand that recognizes toxoplasma gondii and blocks its invasion into host cells”. Org. Bio. Chem. 2019, 17, 4535-4542.

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• Preeti Madhukar Chaudhary, Suraj Toraskar, Rohan Yadav, Akshay Hande, Rina Aradyellin, Raghavendra Kikkeri. - “Multivalent sialoside-A tool to explore the role of sialic acids in biological processes”. Chem-An Asian J. 2019, 1344-1355.

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• Chethan D. Shanthamurthy, Prashant Jain, S. Yehuda, J. T. Monteiro, S. L. Ben-Arye, Vered Padler-karavani, Bernd Lepenies, Raghavendra Kikkeri. - “ABO antigens active tri and disaccharides microarray to evaluate C-type lectin receptor binding preference”. Scientific reports. 2018, 26, 6603.

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• Madhuri Gade, Catherine Alex, S. Yehuda, J. T. Monteiro, S. L. Ben-Arye, Vered Padlerkaravani, Bernd Lepenies, Raghavendra Kikkeri. - Microarray analysis of oligosaccharide-mediated multivalent carbohydrate-protein interactions and their heterogeneity, ChemBioChem. 2018, 19, 1170-1177.

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• Sivakoti Sangabathuni, Raghavendra Vasudeva Murthy, Madhuri Gade, Harikrishna Bavireddi, Suraj Toraskar, Mahesh Sonar, Krishna Ganesh, Raghavendra Kikkeri. - “Modeling Glyco-Collagen Conjugates Using Host-Guest Strategy to Alter Phenotypic Cell Migration and In Vivo Wound Healing” ACS Nano. 2017, 11, 11969-11977.

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• Madhuri Gade, Preeti Madhukar Chaudhary, H. V. Thulasiram, Raghavendra Kikkeri. - “Engineering cell surface glycans with carbohydrate enantiomers to alter bacterial binding and adhesion” ChemistrySelect. 2017, 2, 8865-8869.

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• Suraj Toraskar, Madhuri Gade, Sivakoti Sangabathuni, H. V. Thulasiram, Raghavendra Kikkeri. - “Exploring the influence of shapes and heterogeneity of glyco-gold nanoparticles on bacterial binding for preventing infections” ChemMedChem. 2017, 12, 1116-1124.

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• Sivakoti Sangabathuni, Raghavendra Vasudeva Murthy, Preeti Madhukar Chaudhari, Balamurugan Subramani, Suraj Toraskar, Raghavendra Kikkeri. - “Mapping the glycogold nanoparticles of different shapes toxicity, biodistribution and sequestration in adult zebrafish” Sci. Rep., 2017, 7, 4239.

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• Sivakoti Sangabathuni, Raghavendra Vasudeva Murthy, Preeti Madhukar Chaudhary, Manalee Surve, Anirban Banerjee, Raghavendra Kikkeri. - “Understanding carbohydrate-protein interactions using homologous supramolecular chiral Ru(II)- glyconanoclustures” Nanoscale, 2016, 8, 19696-19702.

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• Rohan Yadav, Shani Ben-Arye, Balamurugan Subramani, Vered Padlar-Karanavani, Raghavendra Kikkeri. - “Screening of Neu5Acα(2-6) gal isomer preferences of siglecs with a sialic acid microarray” Org. Bio. Chem. 2016, 14, 10812-10815.

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• Harikrishna Bavireddi, Raghavendra Vasudeva murthy, Madhuri Gade, Sivakoti Sangabathuni, Raghavendra Kikkeri. “Supramolecular metalloglycodendrimers selectively modulate lectin binding and delivery of Ru(II) complexes into mammalian cells” Org. Bio. Chem. 2016, 14, 10816-10821.

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• Harikrishna Bavireddi, Raghavendra Vasudeva Murthy, Madhuri Gade, Sivakoti Sangabathuni, Catherine, Alex, Preeti Madhukar Chaudhary, Bernd Lepenies, Raghavendra Kikkeri- “Understanding carbohydrate-protein interactions using homologous supramolecular chiral Ru(II)-glyconanclusters” Nanaoscale. 2016, 8, 19696-19702.

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• Sivakoti Sangabathuni, Raghavendra Vasudeva Murthy, Preeti Madhukar Chaudhary, Manalee Surve, Anirban Banerjee, Raghavendra Kikkeri- “Glyco-gold nanoparticle shapes enhance carbohydrate-protein interactions in mammalian cells” Nanoscale, 2016, 7, 12729-12735. 

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• Preeti Madhukar Chaudhary, Madhuri Gade, Rina Arad-Yellin, Sivakoti Sangabathuni, Raghavendra Kikkeri – “Targeting label free carbohydrate-protein interactions for biosensor design” Anal. Methods. 2016, 7, 1024-1027.

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• Raghavendra Vadudeva Murthy, Priya Bharate, Madhuri Gade, Sivakoti Sangabathuni, Raghavendra Kikkeri – “Effect of transition metals on polysialic acid structure and functions” ChemMedChem. 2016, 11, 667-673.

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• Madhuri Gade, Puneet Khandelwal, Sivakoti Sangabathuni, Harikrishna Bavireddi, Raghavendra Vasudeva Murthy, Pankaj Poddar, Raghavendra Kikkeri – “Immobilization of multivalent glycoprobes on gold surfaces for sensing proteins and macrophages” Analyst, 2016, 141, 2250-2258

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• Rohan Yadav, Raghavendra Vasudeva Murthy, Raghavendra Kikkeri – “Sialic acid hydroxamate: a potential antioxidant and inhibitor of metal induced ß-Amyloid aggregates’ ChemBioChem, 2015, 6, 1448-1453.

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• Preeti Madhukar Chaudhary, Raghavendra Vasudeva Murthy, Ajayl Paul, H. V. Thulasiram, Raghavendra Kikkeri – “Assessing the effect of different shapes of glyco-gold nanoparticles on bacterial adhesion and infections”, Chem Commun. 2015, 51, 15669-15672.

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• Preeti Madhukar Chaudhary, Raghavendra Vasudeva Murthy, Raghavendra Kikkeri – “A rationally Designed Peptidomimetic Biosensor for sialic acid on cell surfaces”- Chem. Commun, 2015, 51, 8112-8115.

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• Madhuri Gade, Ajay Paul, Catherine Alex, Devika Choudhary, H. V. Thulasiram, Raghavendra Kikkeri – “Supramolecular scaffolds on glass slides as sugar based rewritable sensors for bacteria” Chem. Commun. 2015, 51, 6346-6349.

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• Raghavendra Vasudeva Murthy, Harikrishna Bavireddi, Madhuri Gade, Raghavendra Kikkeri – “Exploiting the Lactose-GM3 Interaction for drug delivery”- ChemMedChem. 2015, 10, 792-796. 

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• Shadab Ali Khan, Anandita Adak, Raghavendra Vasudeva Murthy, Raghavendra Kikkeri – “Recent advances in the metallo-glycodendrimers and its potential applications”- Inorg. Chem. Acta. 2014, 409, 26-33. Invited review article.

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• Harikrishna Bavireddi, Priya Bharate, Raghavendra Kikkeri- “Use of Boolean and Fuzzy Logics in Lactose Glcocluster Research”- Chem. Commun., 2013, 49, 185-187.

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• Harikrishna Bavireddi, Priya Bharate, Raghavendra Kikkeri- “Probing Carbohydrate-carbohydrate interactions by photoswitchable supramolecular glycoclusters”- Chem. Commun. 2013, 49, 3988-3990.

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• Nahid Azzouz, Faustin Kamena, Paola Laurino, Raghavendra Kikkeri, Corinne Mercier, Marie-France Cesbron-Delauw, J-F Dubremetz, Luisa De Cola, Peter H. Seeberger – “Toxoplasma gondii secretary proteins bind to sulfated heparin structures” – Glycobiology. 2013, 23,106-120.

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• Raghavendra Kikkeri, Vered Padler-Karavani, Sandra Diaz, Andrea Verhagen, Hai Yu, Hongzhi Cao, Martijn A. Langereis, Raoul J.De Groot, Xi Chen, Ajit Varki- “Quantum Dot-FRET based biosensing of sialic acid compositions and linkages in biological samples”, Anal. Chem. 2013, 85, 3864-3870.

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• Harikrishna Bavireddi, Raghavendra Kikkeri – “Glyco-β-Cyclodextrin capped quantum dots: synthesis, cytotoxicity and optical detection of carbohydrate-protein interactions” Analyst. 2012, 137, 5123-5127.

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• Rohan Yadav, Raghavendra Kikkeri- “Exploring the effect of Sialic acid orientation on ligand-receptor interactions” Chem. Commun. 2012, 48, 7265-7267.

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• Rohan Yadav, Raghavendra Kikkeri – “Carbohydrate Functionalized Iron(III) complexes as Biomimetic siderophores Chem. Commun. 2012, 48, 1704-1706.

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• Netta Sella-Passwell, Raghavendra Kikkeri, Tamar Danon, Rina Arad-Yellin, Abraham Shanzer, Irit Sagi – “Metallobodies: antibodies targeted by metalloenzyme functional sites have therapeutic potential” – Nat. Med. 2012, 18, 143-147.

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• Alexander B. Tesler, Giuliano Bellapadrona, Dan Grunstein, Raghavendra Kikkeri, Laila Hossain, Alexander Vaskevich, Peter H. Seeberger, Israel Rubinstein– “LSPR transducers for sensing protein-carbohydrate interactions”. Anal. chem. 2012, 84, 232-240.

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• Dan Grustein, Maha Maglinao, Raghavendra Kikkeri, Paola Laurino, Mayeul Collot, Sung You Hong, Bernd Lepenies and Peter H. Seeberger – “A Sweet, Supramolecular and Fluorescent Six-Legged Hexapus”- J. Am. Chem. Soc. 2011, 133, 13957-13966. “Featured as hot article in JACS”

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• Konstantin Barylyuk, Roman M. Balabin, Dan Grunstein, Raghavendra Kikkeri, Vladimir Frankevich, Peter H. Seeberger, Renato Zenobi – “What happens to hydrophib interactions during transfer from the solution to the gas phase? The case of electrospray-based soft ionization methods” J. Am. Soc. Mass Spectrom. 2011, 22, 1167-1177.

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• Paola Laurino, Raghavendra Kikkeri, Nahid Azzouz, Peter. H. Seeberger – “Photo functionalization Preparation of Glyco-dendronized Polylysine for the Detection of E. coli”. Nano. Lett. 2011, 11, 73-78.

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• Paola Laurino, Raghavendra Kikkeri*, Peter. H. Seeberger – “Continuous Flow Synthesis of Carbohydrate Capped Quantum Dots in Microflow Device”. Nat. Protoc. 2011, 6, 1209-1220, *equal contribution.

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• Gentsch Rafael, Pippig Falko, Nilles Katja, Theato Patrick, Raghavendra Kikkeri, maglinao maha, Lepenies Bernd, Seeberger Peter, Boerner Hans– “Modular approach towards bioactive fiber meshes carrying    oligosaccharides”. Macromolecules, 2010, 43, 9239-9247.

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• Gonçalo J. L. Bernardes, Raghavendra Kikkeri*, Maha Maglinao, Paola Laurino, Mayeul Collot, Sung You Hong, Bernd Lepenies and Peter H. Seeberger – “Design, synthesis and biological evaluation of carbohydrate-functionalized cyclodextrins and liposomes for hepatocyte-specific targeting”. Organic. Biomolecular Chemistry, 2010, 8, 4987-4996. *equal contribution.

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• Raghavendra Kikkeri, Dan Grunstein, Peter. H. Seeberger – “Lectin biosensing using digital analysis of Ru(II)-glycodendrimers” J. Am. Chem. Soc, 2010, 30, 10230-10232.

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• Raghavendra Kikkeri, Xinyu Liu, Alexander Adibekian, Yu-Hsuan Tsai, Peter. H. Seeberger – “Facile synthesis of size dependent Ru(II)- carbohydrate dendrimers via Click Chemistry”. Chem Commun 2010, 46, 2197-2199. “Featured as hot article of February 2010 by Chem. Comm.”

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•  Raghavendra, kikkeri, Paola laurino, Arjan Odedra, Peter H. Seeberger – “Microreactor synthesis of carbohydrate functionalized quantum dots’’ Angew. Chem. Int. Ed. 2010, 49, 2054-2057.

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• Raghavendra Kikkeri, Faustin Kamena, Tarkeshwar Gupta, Laila Hossain, Ganna Gorodyska, Marcus Textor, Peter H. Seeberger – “Ru(II)-glcodendrimers as probes to study lectin-carbohydrate interactions and electrochemically measure mono- and oligosaccharide concentrations”. Langmuir 2010, 26, 1520-1523.

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• Raghavendra, Kikkeri, Bernd Lepenies, Alexander Adibekian, Paola laurino Peter H. Seeberger – “In Vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots” J. Am. Chem. Soc.  2009, 131, 2110-2112.

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• Raghavendra Kikkeri, Inés García-Rubio, Peter. H. Seeberger – “Ru(II)-Carbohydrate dendrimers as photoinduced electron transfer lectin biosensors” Chem. Commun.  2009, 235-237.

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• Raghavendra  Kikkeri, Laila Hossain, Peter. H. Seeberger – “One-pot Supramolecular approach to fluorescent glycodendrimer”. Chem. Commun. 2008,18, 2127-2129.

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• Maya Shvartsman, Raghavendra Kikkeri, Abraham Shanzer, Ioav Z Cabantchik.- "Non transferrinic iron accesses mitochondria by a cytosolic pathway that is unaffected by cytosolic chelators".  Am. J. Physiol. 2007, 293, C1383-C1394.

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• Raghavendra Kikkeri, Hassan Traboulsi, Nicolas Humbert, Elzbieta Gumienna-Kontecka, Rina Arad-Yellin, Galina Melman, Mourad Elhabiri, Anne-Marie Albrecht-Gary, Abraham Shanzer, - "Toward iron sensor: bioinspired tripods on fluorescence phenolic oxazoline coordination site". Inorganic Chemistry. 2007, 46, 2485-2497.

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• Eylon Yavin, Raghavendra Kikkeri, Shosh Gil, Rina Arad-yellin, Ephraim Yavin, Abraham Shanzer -  "Synthesis and biological evaluation of lipophilic iron chelators as protective agents from oxidative stress" Org. Bio. Chem. 2005, 3, 2685-2687.